Tumor targeting with DGEA peptide ligands: A new aromatic peptide amphiphile for imaging cancers

Fu Kai Zhan, Jyun Cheng Liu, Bill Cheng, Yen Chu Liu, Tsung Sheng Lai, Hsin-Chieh Lin*, Mei Yu Yeh

*Corresponding author for this work

研究成果: Article同行評審

9 引文 斯高帕斯(Scopus)

摘要

We report a novel fluorescent bioprobe, tetraphenylethylene-Phe-Asp-Gly-Glu-Ala (TPE-FDGEA), and its self-assembly behavior, photophysical properties, and biocompatibility. The hydrogelator TPE-FDGEA exhibited aggregation-induced emission characteristics, which facilitated imaging of PC-3 human prostate cancer cells, thereby demonstrating the utility of such fluorescent probes for specific labeling of target cells in vitro.

原文English
頁(從 - 到)1060-1063
頁數4
期刊Chemical Communications
55
發行號8
DOIs
出版狀態Published - 1 一月 2019

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