Time-resolved mass spectrometry

Yu-Chie Chen, Pawel L. Urban*

*Corresponding author for this work

研究成果: Review article

32 引文 斯高帕斯(Scopus)

摘要

Mass spectrometry (MS) offers advantages over conventional spectroscopic assays because it enables structural determination of reactants while preserving temporal resolution. The ability to detect short-lived reaction intermediates or labile metabolites makes time-resolved MS (TRMS) measurements an enabling tool for studies of chemical reactions, chemical kinetics and bio-chemical dynamics. High temporal resolution requires careful optimization of the interface, which would enable quenching of the chemical process, ionization and rapid transfer of the analytes into the mass analyzer.We review recent advances in TRMS, and outline the prospects for future developments and applications.

原文English
頁(從 - 到)106-120
頁數15
期刊TrAC - Trends in Analytical Chemistry
44
DOIs
出版狀態Published - 1 一月 2013

指紋 深入研究「Time-resolved mass spectrometry」主題。共同形成了獨特的指紋。

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