Surface-Assisted Laser Desorption/Ionization Mass Spectrometry on Titania Nanotube Arrays

Chun Yuan Lo; Jia Yi Lin; Wei Yu Chen; Cheng Tai Chen; Yu-Chie Chen

doi:10.1016/j.jasms.2008.04.025

Surface-Assisted Laser Desorption/Ionization Mass Spectrometry on Titania Nanotube Arrays

Chun Yuan Lo, Jia Yi Lin, Wei Yu Chen, Cheng Tai Chen, Yu-Chie Chen^*

^*Corresponding author for this work

國立交通大學

研究成果: Article › 同行評審

57 引文斯高帕斯（Scopus）

摘要

Titania nanotube arrays (NTA) generated from anodizing processes are tested as the substrate for surface-assisted laser desorption/ionization mass spectrometry (SALDI MS). The background generated from titania NTA is very low, making the approach suitable for the analysis of small molecules. The upper detectable mass is ∼29 kDa. Homogeneous sample deposition leads to good shot-to-shot reproducibility and suitability for quantitative analysis. Additionally, phosphopeptides can be selectively trapped on the titania NTA substrate, as illustrated by simply depositing a tryptic digest of β-casein followed by titania NTA SALDI MS analysis. The detection limit for small organics and peptides is in low fmol.

原文	English
頁（從 - 到）	1014-1020
頁數	7
期刊	Journal of the American Society for Mass Spectrometry
卷	19
發行號	7
DOIs	https://doi.org/10.1016/j.jasms.2008.04.025
出版狀態	Published - 1 七月 2008

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10.1016/j.jasms.2008.04.025

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