Regioselective synthesis of imidazo[1,5-: A] quinoxalines and methyl N -phenylbenzimidats on an ionic liquid support

Li Hsun Chen, Chih Hsien Kao, Sandip Dhole, Indrajeet J. Barve, Li Ching Shen, Wen-Sheng Chung*, Chung-Ming Sun

*Corresponding author for this work

研究成果: Article

2 引文 斯高帕斯(Scopus)

摘要

An ionic liquid (IL) supported, regioselective synthesis of imidazo[1,5-a]quinoxalines and methyl N-phenylbenzimidats under microwave conditions was reported. The IL-immobilized aromatic amines were reacted with various ketones and aliphatic aldehydes using an unconventional Pictet-Spengler reaction to generate polycyclic imidazo[1,5-a]quinoxalines. Alternatively, aromatic aldehydes afforded auto-oxidized imidazo[1,5-a]quinoxalines first which further converted to novel methyl N-phenylbenzimidats unexpectedly during the cleavage of the IL-support. In the reported strategy, rapidness is achieved through microwave conditions while the IL-support assists purification by simple precipitation.

原文English
頁(從 - 到)76123-76127
頁數5
期刊RSC Advances
6
發行號80
DOIs
出版狀態Published - 1 一月 2016

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