On-Chip Cell Gym

Mitsuhiro Horade*, Chia-Hung Tsai, Hiroaki Ito, Nobuya Higashino, Takayuki Akai, Utako Yokoyama, Yoshihiro Ishikawa, Shinya Sakuma, Fumihito Arai, Makoto Kaneko

*Corresponding author for this work

研究成果: Conference contribution同行評審

3 引文 斯高帕斯(Scopus)

摘要

A novel microfluidic system for applying cyclic pressure to cells during incubation is developed and tested in this work. The cyclic pressure generates stress stimulus to the cells, and is named 'Cell Exercise' in this work. The goal of this paper is to design an 'On-Chip Cell Gym' where we can observe what happens during the cell exercise in real-time. We design the cell gym on a PDMS chip composed of two parallel chamber arrays, so that we can directly observe the difference with and without Cell Exercise. Cells in one group of chamber is cultured under cell exercise mode and the other one is under none cell exercise mode. Dramatic growth of cell stress fibers is observed in the group of cell exercise with respect to the group without any exercise.

原文English
主出版物標題2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017
發行者Institute of Electrical and Electronics Engineers Inc.
頁面603-604
頁數2
ISBN(電子)9781509050789
DOIs
出版狀態Published - 23 二月 2017
事件30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017 - Las Vegas, United States
持續時間: 22 一月 201726 一月 2017

出版系列

名字Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN(列印)1084-6999

Conference

Conference30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017
國家United States
城市Las Vegas
期間22/01/1726/01/17

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