Neurosurgical brain tumor detection based on intraoperative optical intrinsic signal imaging technique: A case report of glioblastoma

Xin Rui Liu, Tien Yu Hsiao, Yun Qian Li, Kai Shih Chiu, Chun Jung Huang, Shan Ji Li, Ching Po Lin, Gang Zhao, Chia Wei Sun*

*Corresponding author for this work

研究成果: Article同行評審

摘要

The delineation of brain tumor margins has been a challenging objective in neurosurgery for decades. Despite the development of various preoperative imaging techniques, the current methodology is still insufficient for clinical practice. We present an intraoperative optical intrinsic signal imaging system for brain tumor surgery and establish a data processing procedure model to localize tumors. From the experimental result of a glioblastoma patient, we observe a relative small oscillation of ΔHbD in tumor region and speculate that vessels in tumor region have poor ability to provide oxygen. We applied the same data processing procedure on the second time data and proclaimed a successful surgery. Figure: Merged ΔHbD image captured prior and posterior to tumor removal.

原文English
文章編號e201900200
期刊Journal of Biophotonics
13
發行號1
DOIs
出版狀態Published - 一月 2020

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