Label-free immunodetection of the cancer biomarker CA125 using high-Δn liquid crystals

Hui Wen Su, Yun Han Lee, Mon Juan Lee*, Yi Chiang Hsu, Wei Lee

*Corresponding author for this work

研究成果: Article同行評審

29 引文 斯高帕斯(Scopus)

摘要

label-free and array-based optical liquid-crystal (LC) immunodetection technique for the detection of CA125 antigen, a protein biomarker most frequently used for ovarian cancer detection, was demonstrated with a nematic LC with larger birefringence (Än) to promote sensitivity in detecting biomolecules. The LC-based immunodetection offers an alternative and sensitive approach for the detection of biomarker proteins, with the potential of replacing conventional immunoassays used in biochemical studies and clinical laboratories

原文English
文章編號077006
期刊Journal of Biomedical Optics
19
發行號7
DOIs
出版狀態Published - 1 一月 2014

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