Coupled waveguide-surface plasmon resonance biosensors constructed with sub-wavelength grating

F. C. Chien*, J. N. Yih, C. Y. Lin, K. L. Lee, Y. M. Chu, Y. C. Mao, W. H. Wang, P. K. Wei, S. J. Chen

*Corresponding author for this work

研究成果: Conference contribution同行評審

摘要

A coupled waveguide-surface plasmon resonance (CWSPR) biosensor constructed with sub-wavelength grating structure is developed and used to analyze biomolecular interaction in real time. The normal incident white light is coupled into the waveguide layer through the sub-wavelength grating, and hence it has an enhanced wave vector to excite the localized surface plasmons on the metal grating surface. The CWSPR biosensor with the surface plasmon resonance (SPR) mode and the waveguide mode not only retains the same sensing sensitivity as that of a conventional SPR device, but also yields sharper dips in the reflectivity spectrum and therefore provides an improved measurement precision. Moreover, without the limitation of a conventional attenuated total reflection coupler and with the help of normal incidence, the system is more flexible and feasible for protein microarray and imaging applications.

原文English
主出版物標題Nanobiophotonics and Biomedical Applications III
DOIs
出版狀態Published - 26 六月 2006
事件Nanobiophotonics and Biomedical Applications III - San Jose, CA, United States
持續時間: 23 一月 200624 一月 2006

出版系列

名字Progress in Biomedical Optics and Imaging - Proceedings of SPIE
6095
ISSN(列印)1605-7422

Conference

ConferenceNanobiophotonics and Biomedical Applications III
國家United States
城市San Jose, CA
期間23/01/0624/01/06

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