Characteristics of pre-S2 region of hepatitis B virus

Szecheng J. Lo*, Ming Lii Chen, Mei Ling Chien, Yan-Hwa Wu Lee

*Corresponding author for this work

研究成果: Article同行評審

2 引文 斯高帕斯(Scopus)


The nucleotide sequence of our cloned HBV DNA (subtype adw) has been determined. When the 165-nucleotide sequence of the pre-S2 region was compared with 7 other published sequences (subtypes adw, adr, ayw, and adyw), we found 38 nucleotide substitutions among different subtypes and 4 (adr) or 6 (adw and ayw) substitutions within the same subtype. Analysis of the predicted amino acid sequence from the known nucleotide sequences indicates that: 1) there are 20 amino acid substitutions, 2) the longest conserved amino acid sequence is located between amino acids 23 to 34, and 3) the 54th amino acid is identical within the same subtype but varies in different subtypes.

頁(從 - 到)382-388
期刊Biochemical and Biophysical Research Communications
出版狀態Published - 13 三月 1986

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