Angiogenesis inhibitor epoxyquinol A: Total synthesis and inhibition of transcription factor NF-κB

Chaomin Li, Sujata Bardhan, Emily A. Pace, Mei-Chih Liang, Thomas D. Gilmore, John A. Porco

研究成果: Article同行評審

72 引文 斯高帕斯(Scopus)

摘要

equation presented The asymmetric synthesis of the natural product (+)-epoxyquinol A (1) and related epoxyquinoid dimers, employing a cascade oxidation/ electrocyclization/Diels-Alder dimerization sequence, is reported. In addition, we show that 1 and related molecules inhibit activation of the transcription factor NF-κB.

原文English
頁(從 - 到)3267-3270
頁數4
期刊Organic Letters
4
發行號19
DOIs
出版狀態Published - 19 九月 2002

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