Visible light absorption spectroscopy for rapid screening of synovial fluid

Han Wen Guo, Chao Yuan Yu, Hsing Wen Wang, Chia Yen Lee*, Chia-Wei Sun

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In diagnosis of arthritis, severity level of synovial inflammation is one of important information to discriminate arthritis types. In this study, we measured the visible absorption spectra of synovial fluid from arthritis patients and found a stronger absorption band between 380 to 450 nm. Then, the measured optical density (OD) of synovial fluid at 420 nm (OD420) was used to estimate severity level of synovial inflammation and compare with clinical classification of inflammation synovial fluid by counting white blood cells (WBCs) number of synovial fluid. In our experimental result, OD420 of synovial fluid concomitantly increased with the severity level of synovial inflammatory. Therefore, we suggest the optical detection of OD420 of synovial fluid can be an indicator to determine severity level of synovial inflammation.

Original languageEnglish
Title of host publicationProceedings - 2014 International Symposium on Computer, Consumer and Control, IS3C 2014
PublisherIEEE Computer Society
Pages931-933
Number of pages3
ISBN (Print)9781479952779
DOIs
StatePublished - 1 Jan 2014
Event2nd International Symposium on Computer, Consumer and Control, IS3C 2014 - Taichung, Taiwan
Duration: 10 Jun 201412 Jun 2014

Publication series

NameProceedings - 2014 International Symposium on Computer, Consumer and Control, IS3C 2014

Conference

Conference2nd International Symposium on Computer, Consumer and Control, IS3C 2014
CountryTaiwan
CityTaichung
Period10/06/1412/06/14

Keywords

  • absorption spectroscopy
  • arthritis
  • synovial fluid
  • synovial inflammatory severity
  • white blood cell

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  • Cite this

    Guo, H. W., Yu, C. Y., Wang, H. W., Lee, C. Y., & Sun, C-W. (2014). Visible light absorption spectroscopy for rapid screening of synovial fluid. In Proceedings - 2014 International Symposium on Computer, Consumer and Control, IS3C 2014 (pp. 931-933). [6846036] (Proceedings - 2014 International Symposium on Computer, Consumer and Control, IS3C 2014). IEEE Computer Society. https://doi.org/10.1109/IS3C.2014.244