Vinyl radical cyclization onto imino group. Selective 6-endo cyclization onto aldimines leading to 3-methylenepiperidines

Ilhyong Ryu*, Shin ichi Ogura, Satoshi Minakata, Mitsuo Komatsu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations

Abstract

When 5-exo/6-endo type of vinyl radical cyclization onto aldimine N=C bond was examined using tin hydride mediated radical reaction conditions, selective 6-endo cyclization took place to lead to 3-methylenepiperidines. On the other hand, vinyl radical cyclization onto ketimine N=C bond did not take place.

Original languageEnglish
Pages (from-to)1515-1518
Number of pages4
JournalTetrahedron Letters
Volume40
Issue number8
DOIs
StatePublished - 19 Feb 1999

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