The catalytic reactivity of Cu-ZSM-5 zeolite for NOx reduction was studied using acetone solvent as the reducing agent by a fixed bed continuous flow reactor system. The catalytic reactivity of Cu-ZSM-5 was also compared with non-porous copper supported metal oxide catalysts such as CuO/SiO2 and CuO/Al2O3. The NO conversion over Cu-ZSM-5 catalyst was increased with increasing reaction temperature. The Cu-ZSM-5 catalysts showed a better performance in the VOC-SCR deNOx process in terms of the simultaneous removals of NOx and organic solvent vapors as compared to those of CuO/Al2O3 and CuO/SiO2. Cu/ZSM-5 and CuO/Al2O3 catalyst showed almost similar acetone oxidation activity with respect to reaction temperature. However, CuO/SiO2 catalyst was less active as compard to those of CuO/Al2O3 and Cu-ZSM-5. This is an abstract of a paper presented at the 101st AWMA Annual Conference and Exhibition (Portland, OR 6/24-27/2008).