Abstract
Granulocytes are a group of white blood cells belonging to the innate immune system in human and in murine in which eosinophils play an important role in worm infection-induced inflammation. The migration of these cells is well characterized and has been separated into four steps: rolling, adhesion, transendothelial migration, and chemotaxis, however, the physical characteristics of the chemotactic force to eosinophils from worm component remain largely unknown. Note that optical tweezers are featured in the manipulation of a single cell and the measurement of biological forces. Therefore, we propose to use optical tweezers to examine the chemotactic force to a eosinophil from a T. canis lavae preparation in terms of distance during the migration of eosinophil.
Original language | English |
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Article number | 59301R |
Pages (from-to) | 1-9 |
Number of pages | 9 |
Journal | Proceedings of SPIE - The International Society for Optical Engineering |
Volume | 5930 |
DOIs | |
State | Published - 1 Dec 2005 |
Event | Optical Trapping and Optical Micromanipulation II - San Diego, CA, United States Duration: 31 Jul 2005 → 4 Aug 2005 |
Keywords
- Chemotacfic force
- Eosinophil
- Optical tweezers