Using impedance biosensors to distinguish the PC12 cells adhesion and differentiation

Chen Chia Chen, Shan Yu Lin, Jeng-Tzong Sheu*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

Some properties of living cells are associated with cell adhesion and cell spreading process. Traditional way to monitor cells' morphological changes is usually the use of optical microscope. Biosensors provide an alternative to automatically monitor cell adhesion and spreading process. This study utilized microelectrodes array based impedance biosensors to record cells attachment and differentiation via changes of impedance. The results were confirmed with the images of optical microscope. Based on the electrical model proposed, cell adhesion and differentiation can be clearly identified without any additional biochemical tests.

Original languageEnglish
Title of host publicationNEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
Pages813-816
Number of pages4
DOIs
StatePublished - 4 Oct 2011
Event6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011 - Kaohsiung, Taiwan
Duration: 20 Feb 201123 Feb 2011

Publication series

NameNEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

Conference

Conference6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011
CountryTaiwan
CityKaohsiung
Period20/02/1123/02/11

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