Using a Low Fluence Q-Switched 532/1064-nm Nd: YAG Laser for Facial Skin Depigmentation in Asian Patients: Outcome and Complication Profile Analysis: Outcome and complication profile analysis

Jen Hsiang Shen, Chang Cheng Chang*, Yu Tsung Chen, Chao Jen Hsih, Hsin Huang, Bor-Shyh Lin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Background and Objectives: Low fluence Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers are widely applied for facial depigmentation. Nonetheless, few reports analyze the general outcome, complications, of single and combined therapy of 532/1064-nm Nd:YAG lasers in Asian patients with Fitzpatrick type IV skin. Study Design/Materials and Methods:We retrospectively reviewed all consecutive patients who completed 5 consecutive sessions at 1-month intervals of treatment with 1064-nm (spot size: 5-7 mm, 1.5-2.0 J/cm2) or combined with 532-nm (spot size, 2-3 mm; 0.5-1.5 J/cm2) Nd:YAG laser (Laseroptek, Korea) from October 2011 to March 2013. The patients, laser surgeon, and 3 blinded reviewers assessed the outcomes and complications. Improvement was graded as follows: 1, 0%-25%; 2, 26%-50%; 3, 51%-75%; 4, 76-90%; and 5, greater than 90%. Postinflammatory hyperpigmentation (PIH) was documented according to the severity (1, slight; 2, moderate; 3, severe; and 4, extreme).Other post-laser side effects were also documented (eg, scaling, dryness, erythema, and pruritus). Results: Four male patients and 37 female patients were included with a mean age of 38.5 years (SD, 10.1 years). There were no significant differences on patients', surgeon's, or blinded reviewers' improvement gradings. (4.11 ± 0.62 vs 4.30 ± 0.46, P=0.54; 3.88 ± 0.66 vs 3.89 ± 0.31, P=0.50; 3.30 ± 0.69 vs 3.74 ± 0.38, P=0.34). Transient minor side effect occurred as follows: erythema in 9 (22%), pruritus in 7 (17%), dryness in 6 (15%), and scaling in 6 (15%). There was no risk difference in these side effects between groups. The PIH scores were slight in 10 patients (4 in single and 6 in combined), severe in 4 (3 in single and 1 in combined), and extreme in 1 (single therapy). The PIH incidence also did not differ (33.3%, 35.3%; P=0.58). Conclusions: We reported satisfactory outcomes after low-fluence Q-switched sole 1064-nmor combined 532/1064-nmtherapy. The outcome and complication profiles did not differ between the groups. The PIH incidence was not low, but usually transient. The incidence of severe or extreme PIH was rare.

Original languageEnglish
Pages (from-to)S32-S35
JournalAnnals of Plastic Surgery
Volume77
Issue number1
DOIs
StatePublished - 1 Aug 2016

Keywords

  • Asian patients
  • Laser complications
  • Low fluence Q-switched Nd:YAG laser
  • Postinflammatory hyperpigmentation

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