Tumor targeting with DGEA peptide ligands: A new aromatic peptide amphiphile for imaging cancers

Fu Kai Zhan, Jyun Cheng Liu, Bill Cheng, Yen Chu Liu, Tsung Sheng Lai, Hsin-Chieh Lin*, Mei Yu Yeh

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

We report a novel fluorescent bioprobe, tetraphenylethylene-Phe-Asp-Gly-Glu-Ala (TPE-FDGEA), and its self-assembly behavior, photophysical properties, and biocompatibility. The hydrogelator TPE-FDGEA exhibited aggregation-induced emission characteristics, which facilitated imaging of PC-3 human prostate cancer cells, thereby demonstrating the utility of such fluorescent probes for specific labeling of target cells in vitro.

Original languageEnglish
Pages (from-to)1060-1063
Number of pages4
JournalChemical Communications
Volume55
Issue number8
DOIs
StatePublished - 1 Jan 2019

Fingerprint Dive into the research topics of 'Tumor targeting with DGEA peptide ligands: A new aromatic peptide amphiphile for imaging cancers'. Together they form a unique fingerprint.

Cite this