Three-dimensional pH microprobing with an optically-manipulated fluorescent particle

Keiji Sasaki*, Zhong You Shi, Raoul Kopelman, Hiroshi Masuhara

*Corresponding author for this work

Research output: Contribution to journalArticle

60 Scopus citations


A novel pH microprobe has been developed, which makes it possible to measure inhomogencous pH distributions with submicrometer three-dimensional resolution. A polyacrylamide particle incorporated with pH-sensitive fluorescein-acrylamide is manipulated with a laser trapping technique. It is demonstrated that the local pH in a water/glass interface is different from that of bulk water.

Original languageEnglish
Pages (from-to)141-142
Number of pages2
JournalChemistry Letters
Issue number2
StatePublished - 1 Jan 1996

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