Therapeutic hypothermia for neonates with hypoxic ischemic encephalopathy

Ming Chou Chiang, Yuh-Jyh Jong, Chyi-Her Lin

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


Therapeutic hypothermia (TH) is a recommended regimen for newborn infants who are at or near term with evolving moderate-to-severe hypoxic ischemic encephalopathy (HIE). The Task Force of the Taiwan Child Neurology Society and the Taiwan Society of Neonatology, held a joint meeting in 2015 to establish recommendations for using TH on newborn patients with HIE. Based on current evidence and experts' experiences, this review article summarizes the key points and recommendations regarding TH for newborns with HIE, including: (1) selection criteria for TH; (2) choices of method and equipment for TH; (3) TH prior to and during transport; (4) methods for temperature maintenance, monitoring, and rewarming; (5) systemic care of patients during TH, including the care of respiratory and cardiovascular systems, management of fluids, electrolytes, and nutrition, as well as sedation and drug metabolism; (6) monitoring and management of seizures; (7) neuroimaging, prognostic factors, and outcomes; and (8) adjuvant therapy for TH. Copyright (C) 2017, Taiwan Pediatric Association. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license.
Original languageEnglish
Pages (from-to)475-483
Number of pages9
JournalPediatrics and Neonatology
StatePublished - Dec 2017


  • hyppxic ischemic encephalopathy; neonate; patient Care; perinatal asphyxia; therapeutic hypothermia

Fingerprint Dive into the research topics of 'Therapeutic hypothermia for neonates with hypoxic ischemic encephalopathy'. Together they form a unique fingerprint.

Cite this