Synthesis of 2,3-disubstituted indenones by cobalt-catalyzed [3+2] annulation of: O -methoxycarbonylphenylboronic acid with alkynes

Mitsuhiro Ueda*, Tamami Ueno, Yuki Suyama, Ilhyong Ryu

*Corresponding author for this work

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Treatment of alkynes with o-methoxycarbonylphenylboronic acid in the presence of a cobalt catalyst resulted in the corresponding 2,3-disubstituted indenones in good yields. Excellent regioselectivities were observed, when silyl aryl alkynes were used. The intermediate 3-silyl-2-aryl-substituted indenones were converted to 2,3-diaryl indenones by a three-step protocol involving C-Si bromination and Suzuki-Miyaura coupling reaction.

Original languageEnglish
Pages (from-to)13237-13240
Number of pages4
JournalChemical Communications
Volume52
Issue number90
DOIs
StatePublished - 1 Jan 2016

Fingerprint Dive into the research topics of 'Synthesis of 2,3-disubstituted indenones by cobalt-catalyzed [3+2] annulation of: O -methoxycarbonylphenylboronic acid with alkynes'. Together they form a unique fingerprint.

  • Cite this