Abstract
The potential of the oxy-Favorskii rearrangement to form branched cis-fused bicyclic ethers was explored. Both tertiary and quaternary centers were constructed in highly stereospecific manners. Methanol and primary amines were effective nucleophiles for the rearrangement. The total synthesis of (±)-communiol E was achieved based on this method.
Original language | English |
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Pages (from-to) | 7096-7103 |
Number of pages | 8 |
Journal | Journal of Organic Chemistry |
Volume | 76 |
Issue number | 17 |
DOIs | |
State | Published - 2 Sep 2011 |