State-of-the-Art on Functional Titanium Dioxide-Integrated Nano-Hybrids in Electrical Biosensors

Sh Nadzirah*, Subash C.B. Gopinath, N. A. Parmin, Azrul Azlan Hamzah, Mohd Ambri Mohamed, Edward Yi Chang, Chang Fu Dee

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Biosensors operating based on electrical methods are being accelerated toward rapid and efficient detection that improve the performance of the device. Continuous study in nano- and material-sciences has led to the inflection with properties of nanomaterials that fit the trend parallel to the biosensor evolution. Advancements in technology that focuses on nano-hybrid are being used to develop biosensors with better detection strategies. In this sense, titanium dioxide (TiO2) nanomaterials have attracted extensive interest in the construction of electrical biosensors. The formation of TiO2 nano-hybrid as an electrical transducing material has revealed good results with high performance. The modification of the sensing portion with a combination (nano-hybrid form) of nanomaterials has produced excellent sensors in terms of stability, reproducibility, and enhanced sensitivity. This review highlights recent research advancements with functional TiO2 nano-hybrid materials, and their victorious story in the construction of electrical biosensors are discussed. Future research directions with commercialization of these devices and their extensive utilizations are also discussed.

Original languageEnglish
JournalCritical Reviews in Analytical Chemistry
DOIs
StateAccepted/In press - 2020

Keywords

  • Electrochemical biosensor
  • electronic transducer
  • nanocomposite
  • organic–inorganic materials
  • quantitative biosensor

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