Spectroscopic study of bio-functionalized nanodiamonds

P. H. Chung, E. Perevedentseva, J. S. Tu, Chia-Ching Chang, C. L. Cheng*

*Corresponding author for this work

Research output: Contribution to journalArticle

168 Scopus citations

Abstract

Nano-scale materials with attached biomolecules on the surface can be used as bioprobes in cell and tissue analysis. The conjugation of these nanoparticles with biomolecules is one of the key steps in the development of bioprobes. In this work nanometer-sized diamonds (5 and 100 nm) are functionalized and conjugated with protein lysozyme via physical adsorption. The process of creating functional groups on the nanodiamond surface is studied using Fourier Transform Infrared-spectroscopy (FTIR). The conjugation of nanodiamonds with biomolecules and nanodiamond-biomolecule interaction are analyzed with UV/VIS and FTIR spectroscopy.

Original languageEnglish
Pages (from-to)622-625
Number of pages4
JournalDiamond and Related Materials
Volume15
Issue number4-8
DOIs
StatePublished - 1 Apr 2006

Keywords

  • Biomedical applications
  • Nanodiamonds
  • Sensors
  • Surface characterization

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