Room temperature negative differential resistance in DNA-based molecular devices

Peng Chung Jangjian, Tzeng Feng Liu, Mei Yi Li, Ming Shih Tsai, Chia-Ching Chang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


A molecular device fabricated from metallic deoxyribonucleic acid (M-DNA) exhibits a negative differential resistance (NDR) behavior. When two gold electrodes were connected by Ni2+ -chelated DNA, which was converted from λ-DNA, not only was the conductivity of DNA improved, but a NDR device was formed as a full cyclic voltage sweep was applied to measure its current versus voltage characteristics at room temperature and in an ambient environment. Such electronic characteristics of a M-DNA device may have been caused by the redox reactions of Ni ions. This finding provides a simple way to construct electrical nanodevices from biological molecules.

Original languageEnglish
Article number043105
JournalApplied Physics Letters
Issue number4
StatePublished - 9 Feb 2009

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