Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: A colon-rectal cancer antigen determinant

Kwok-Kong Mong, Chi Huey Wong

Research output: Contribution to journalArticle

92 Scopus citations

Abstract

The stereospecific synthesis of a tumor-related carbohydrate antigenic hapten, Lewis Y, from three basic building units 1 - 3 has been achieved by a reactivity-based one-pot strategy. RRV = relative reactivity value.

Original languageEnglish
Pages (from-to)4087-4090
Number of pages4
JournalAngewandte Chemie - International Edition
Volume41
Issue number21
DOIs
StatePublished - 4 Nov 2002

Keywords

  • Antigens
  • Antitumor agents
  • Glycosylation
  • Oligosaccharides
  • Reactivity-based synthesis

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