Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: A colon-rectal cancer antigen determinant

Kwok-Kong Mong; Chi Huey Wong

doi:10.1002/1521-3773(20021104)41:21<4098::AID-ANIE4098>3.0.CO;2-P

Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: A colon-rectal cancer antigen determinant

Kwok-Kong Mong, Chi Huey Wong

Department of Applied Chemistry

Research output: Contribution to journal › Article

92 Scopus citations

Abstract

The stereospecific synthesis of a tumor-related carbohydrate antigenic hapten, Lewis Y, from three basic building units 1 - 3 has been achieved by a reactivity-based one-pot strategy. RRV = relative reactivity value.

Original language	English
Pages (from-to)	4087-4090
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	41
Issue number	21
DOIs	https://doi.org/10.1002/1521-3773(20021104)41:21<4098::AID-ANIE4098>3.0.CO;2-P
State	Published - 4 Nov 2002

Keywords

Antigens
Antitumor agents
Glycosylation
Oligosaccharides
Reactivity-based synthesis

Access to Document

10.1002/1521-3773(20021104)41:21<4098::AID-ANIE4098>3.0.CO;2-P

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Mong, K-K., & Wong, C. H. (2002). Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: A colon-rectal cancer antigen determinant. Angewandte Chemie - International Edition, 41(21), 4087-4090. https://doi.org/10.1002/1521-3773(20021104)41:21<4098::AID-ANIE4098>3.0.CO;2-P

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