Push/pull inequality based high-speed on-chip mixer enhanced by wettability

Toshio Takayama*, Naoya Hosokawa, Chia Hung Dylan Tsai, Makoto Kaneko

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


In this paper, a high-speed on-chip mixer using two effects is proposed, i.e., push/pull inequality and wettability. Push/pull inequality and wettability are effective for generating a rotational fluid motion in the chamber and for enhancing the rotational speed by reducing the viscous loss between the liquid and channel wall, respectively. An on-chip mixer is composed of three components, a microfluidic channel for making the main fluid flow, a circular chamber connected to the channel for generating a rotational flow, and an actuator connected at the end of the channel allowing a push/pull motion to be applied to the liquid in the main channel. The flow patterns in the chamber under push/pull motions are nonreversible for each motion and, as a result, produce one-directional torque to the fluid in the circular chamber. This nonreversible motion is called push/pull inequality and eventually creates a swirling flow in the chamber. Using hydrophilic treatments, we executed the experiment with a straight channel and a circular chamber to clarify the mixing characteristics at different flow speeds. According to the results, it is confirmed that the swirling velocity under appropriately tuned wettability is 100 times faster than that without tuning.

Original languageEnglish
Article number950
Issue number10
StatePublished - Oct 2020


  • Hydrophilic treatment
  • Nonreversible flow pattern
  • On-chip mixer
  • Push/pull inequality
  • Surfactant
  • Wettability

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