Preparation of a protected 3-deoxy-d-manno-oct-2-ulosonate glycal donor for the synthesis of β-KDO-containing oligosaccharides

Tapan Kumar Pradhan, Chun Cheng Lin, Kwok-Kong Mong*

*Corresponding author for this work

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

A practical method for the synthesis of KDO glycal donors was developed. The prepared KDO donors exhibited excellent disastereoselectivity of glycosylation in a CH2Cl2-CH3CN solvent mixture, which was found to be associated with the isopropylidene protection at the C-4 and C-5 hydroxyls. The synthetic use of the KDO donor was demonstrated in the preparation of β-KDO-containing oligosaccharides.

Original languageEnglish
Pages (from-to)1474-1477
Number of pages4
JournalOrganic Letters
Volume16
Issue number5
DOIs
StatePublished - 7 Mar 2014

Fingerprint Dive into the research topics of 'Preparation of a protected 3-deoxy-d-manno-oct-2-ulosonate glycal donor for the synthesis of β-KDO-containing oligosaccharides'. Together they form a unique fingerprint.

  • Cite this