Preparation and characterization of gelatin/oligomeric proanthocyanidins composite microspheres

Ching Wen Lou, Jin-Jia Hu*, Chao Chiung Huang, Shih Yu Huang, Hsiu Hui Yeh, Jia Horng Lin

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Gelatin is a heterogeneous mixture of single or multi-stranded polymers made of amino acids. Its film formability, air permeability, biocompatibility, and hemostatic activity render it appropriate for wound dressing. In this study, we used a syringe to drop gelatin solution into oligomeric proanthocyanidins solution to prepare the composite microspheres. Physical properties of the composite microsphere, such as swelling, stability in water, contact angle, and Fourier transform infrared spectroscopy were examined. We aimed at investigating its potential use in promoting wound healing along with wound dressings. The greatest swelling (1480 %) of the gelatin/OPC composite microsphere was achieved in 10 min. The composite microspheres dissolved 90% in the first 60 min during water stability test. Therefore, the developed composite microsphere has great hydrophilic and can be used in biomedical applications.

Original languageEnglish
Title of host publicationApplications of Engineering Materials
Pages132-135
Number of pages4
DOIs
StatePublished - 12 Aug 2011
Event2011 International Conference on Advanced Engineering Materials and Technology, AEMT 2011 - Sanya, China
Duration: 29 Jul 201131 Jul 2011

Publication series

NameAdvanced Materials Research
Volume287-290
ISSN (Print)1022-6680

Conference

Conference2011 International Conference on Advanced Engineering Materials and Technology, AEMT 2011
CountryChina
CitySanya
Period29/07/1131/07/11

Keywords

  • Composite microsphere
  • Gelatin
  • Oligomeric proanthocyanidins
  • Swelling

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