Photonic crystal micropost as a microarray platform

Chih Wei Chang, Cheng-Sheng Huang

Research output: Contribution to journalArticle

Abstract

This study demonstrates a photonic crystal micropost (PCMP) substrate for microarray applications. The substrate comprises an array of circular MPs with a PC on top of these MPs. This substrate enables biomolecule-containing droplets to form a composite contact upon deposition, thus allowing biomolecules to be attached on only the MPs, forming spots. When the device (PC) is excited on resonance, the electric field intensity is enhanced on only the top surface of the MPs. This enables the fluorescence intensities to be enhanced up to 5.50x; principally, this enhancement does not engender an increase in the background (intensity outside MP or spots) and noise intensities. The PCMP substrate enhances the spot intensity and minimizes the background intensity, enabling the detection of lower concentration analytes.

Original languageEnglish
Pages (from-to)2954-2964
Number of pages11
JournalOptics Express
Volume24
Issue number3
DOIs
StatePublished - 8 Feb 2016

Fingerprint Dive into the research topics of 'Photonic crystal micropost as a microarray platform'. Together they form a unique fingerprint.

  • Cite this