Pd-Catalyzed Redox-Neutral C-N Coupling Reaction of Iminoquinones with Electron-Deficient Alkenes without External Oxidants: Access of Tertiary (E)-Enamines and Application to the Synthesis of Indoles and Quinolin-4-ones

Raveendra Jillella, Selvam Raju, Huan Chang Hsiao, Day Shin Hsu, Shih Ching Chuang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

A novel and efficient reductive N-alkenylation of iminoquinones with electron-deficient olefins has been successfully developed by Pd(II)-catalyzed redox-neutral reactions, which provides a synthesis of tertiary (E)-enamines. We further demonstrate that the tertiary enamines can be converted to multifarious N-heterocyclic compounds, indoles, and quinolones in good yields.

Original languageEnglish
JournalOrganic Letters
DOIs
StateAccepted/In press - 2020

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