Pattern discovery from patient controlled analgesia demand behavior

Yuh-Jyh Hu*, Tien Hsiung Ku

*Corresponding author for this work

Research output: Contribution to journalArticle

1 Scopus citations


Unlike previous research on patient controlled analgesia, this study explores patient demand behavior over time. We apply clustering methods to disclose demand patterns among patients over the first 24. h of analgesic medication after surgery. We consider demographic, biomedical, and surgery-related data in statistical analyses to determine predictors for patient demand behavior, and use stepwise regression and Bayes risk analysis to evaluate the influence of demand pattern on analgesic requirements. We identify three demand patterns from 1655 patient controlled analgesia request log files. Statistical tests show correlations of gender (p=0022), diastolic blood pressure (p=025), surgery type (p=0028), and surgical duration (p<0095) with demand patterns. Stepwise regression and Bayes risk analysis show demand pattern plays the most important role in analgesic consumption prediction (p=0.E+0). This study suggests analgesia request patterns over time exist among patients, and clustering can disclose demand behavioral patterns.

Original languageEnglish
Pages (from-to)1005-1011
Number of pages7
JournalComputers in Biology and Medicine
Issue number10
StatePublished - 1 Oct 2012


  • Behavioral pattern
  • Clustering
  • PCA demand
  • Pain management
  • Patient controlled analgesia

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