One-pot synthesis of triazoloquinazolinones via copper- catalyzed tandem click and intramolecular C-H amidation

Manikandan Selvaraju, Chung-Ming Sun*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

A novel and highly efficient copper-catalyzed tandem synthesis of triazoloquinazolinones is explored. The synthetic strategy involves a sequential one-pot click reaction followed by aerobic intramolecular C-H amidation. Two distinct and important transformations were carried out in one-pot by employing a single cost-effective copper catalyst. The milder, rapid and ligand-free reaction conditions as well as a broader substrate scope are the salient features of this novel protocol.

Original languageEnglish
Pages (from-to)1329-1336
Number of pages8
JournalAdvanced Synthesis and Catalysis
Volume356
Issue number6
DOIs
StatePublished - 14 Apr 2014

Keywords

  • C-H amidation
  • copper-catalyzed reaction
  • one-pot protocol
  • tandem reactions
  • triazoloquinazolinones

Fingerprint Dive into the research topics of 'One-pot synthesis of triazoloquinazolinones via copper- catalyzed tandem click and intramolecular C-H amidation'. Together they form a unique fingerprint.

Cite this