Observation of cell pinball through high speed switching between reflection interference and phase contrast

Ryo Murakami*, Akihisa Yamamoto, Hiroaki Ito, Chia-Hung Tsai, Mitsuhiro Horade, Motomu Tanaka, Makoto Kaneko

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

'Cell Pinball' is a phenomenon whereby rotating red blood cells (RBCs) move like pinballs inside a microfluidic channel where the cell inertia is negligible. The goal of this paper is to discuss the location of the actual rotational axis through the careful comparison between the contour and contact shapes of a moving RBC. By switching the reflection interference contrast (RIC) and the phase contrast (PhC) microscopes with the mean cycle time of 0.440 s, we found that the difference between the trajectories of each centroid of the visualized RBC by RIC and PhC is less than 0.8 μm.

Original languageEnglish
Title of host publication2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1337-1338
Number of pages2
ISBN (Electronic)9781509050789
DOIs
StatePublished - 23 Feb 2017
Event30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017 - Las Vegas, United States
Duration: 22 Jan 201726 Jan 2017

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Conference

Conference30th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2017
CountryUnited States
CityLas Vegas
Period22/01/1726/01/17

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    Murakami, R., Yamamoto, A., Ito, H., Tsai, C-H., Horade, M., Tanaka, M., & Kaneko, M. (2017). Observation of cell pinball through high speed switching between reflection interference and phase contrast. In 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems, MEMS 2017 (pp. 1337-1338). [7863667] (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MEMSYS.2017.7863667