Noninvasive in vivo millimeter-wave measurements of glucose: First results in human subjects

Peter H. Siegel, Adrian Tang, Rod Kim, Gabriel Virbila, Mau-Chung Chang, Victor Pikov

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations

Abstract

We present initial data on noninvasive millimeter-wave tracking of glucose levels in human subjects. Measurements were made using three separate test systems, all giving similar results: (1) a K-band (WR42) rectangular waveguide clamp coupled to a direct detector to measure transmission magnitude through the upper ear between 15 and 25 GHz; (2) a K-band waveguide clamp connected to a vector network analyzer to measure magnitude and phase of transmitted power through the ear lobe; and (3) a Ka-band rectangular waveguide clamp operating from 26-36 GHz also recording complex transmission coefficients through the ear lobe. A novel compact CMOS heterodyne transceiver operating at 19-21 GHz was also tested, but failed to show sufficient antenna-to-antenna power coupling to produce useful results. Data was collected during a standard oral glucose tolerance test (OGTT) in one healthy volunteer and correlated with blood glucose measurements using a commercial glucometer. Preliminary results show good correlation between blood glucose measurements (invasive) and both magnitude and phase of millimeter-wave transmission (non-invasive) through the skin, and are in accordance with our earlier animal experiments conducted on anesthetized rats.

Original languageEnglish
Title of host publication2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2017
PublisherIEEE Computer Society
ISBN (Electronic)9781509060481
DOIs
StatePublished - 12 Oct 2017
Event42nd International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2017 - Cancun, Quintana Roo, Mexico
Duration: 27 Aug 20171 Sep 2017

Publication series

NameInternational Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz
ISSN (Print)2162-2027
ISSN (Electronic)2162-2035

Conference

Conference42nd International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2017
CountryMexico
CityCancun, Quintana Roo
Period27/08/171/09/17

Fingerprint Dive into the research topics of 'Noninvasive in vivo millimeter-wave measurements of glucose: First results in human subjects'. Together they form a unique fingerprint.

Cite this