Abstract
Although Candida albicans cph1/cph1 efg1/efg1 mutant cells are not lethal to mice, they proliferated in infected mice instead of simply being cleared by the host immune system. Here, we have shown that the cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by the lethal wild-type Candida albicans cells. Our results further indicate that a second dose of the cph1/cph1 efg1/efg1 mutant did not boost the degree of protection. (c) 2008 The British Mycological Society. Published by Elsevier Ltd. All rights reserved.
Original language | English |
---|---|
Pages (from-to) | 388-390 |
Number of pages | 3 |
Journal | Mycological Research |
DOIs | |
State | Published - Mar 2009 |