Neurosurgical brain tumor detection based on intraoperative optical intrinsic signal imaging technique: A case report of glioblastoma

Xin Rui Liu, Tien Yu Hsiao, Yun Qian Li, Kai Shih Chiu, Chun Jung Huang, Shan Ji Li, Ching Po Lin, Gang Zhao, Chia Wei Sun*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

The delineation of brain tumor margins has been a challenging objective in neurosurgery for decades. Despite the development of various preoperative imaging techniques, the current methodology is still insufficient for clinical practice. We present an intraoperative optical intrinsic signal imaging system for brain tumor surgery and establish a data processing procedure model to localize tumors. From the experimental result of a glioblastoma patient, we observe a relative small oscillation of ΔHbD in tumor region and speculate that vessels in tumor region have poor ability to provide oxygen. We applied the same data processing procedure on the second time data and proclaimed a successful surgery. Figure: Merged ΔHbD image captured prior and posterior to tumor removal.

Original languageEnglish
Article numbere201900200
JournalJournal of Biophotonics
Volume13
Issue number1
DOIs
StatePublished - Jan 2020

Keywords

  • brain tumor surgery
  • optical intrinsic signal
  • surgery guiding

Fingerprint Dive into the research topics of 'Neurosurgical brain tumor detection based on intraoperative optical intrinsic signal imaging technique: A case report of glioblastoma'. Together they form a unique fingerprint.

  • Cite this