Multifunctional Fe3O4 @Au nanoeggs as photothermal agents for selective killing of nosocomial and antibiotic-resistant bacteria

Wei Chieh Huang*, Pei Jane Tsai, Yu-Chie Chen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

156 Scopus citations

Abstract

A study was conducted to demonstrate the use of Fe3O 4@Au nanoeggs, as photothermal agents for selective killing of nosocomial and antibiotic-resistant bacteria. The study demonstrated that the M(H) hysteresis curve for the nanoparticles (NPs) was completely reversible, indicating that these NPs exhibited superparamagnetic characteristics. It was also demonstrated that the saturation moment per unit mass for the Fe 3O4@Au nanoeggs was 0.04 emu g-1 at 10000 Oe. It was also expected that the Fe3O4@Au nanoegg-targeted bacteria will have significantly larger magnetic, despite each nanoegg having small magnetic moment. Thymol blue was employed in Tris buffer as a temperature indicator, to evaluate the photothermal behavior of the Fe3O 4@Au nanoeggs.

Original languageEnglish
Pages (from-to)51-56
Number of pages6
JournalSmall
Volume5
Issue number1
DOIs
StatePublished - 1 Jan 2009

Keywords

  • Antibiotics
  • Bacteria
  • Magnetic properties
  • Photochemistry

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