TY - GEN
T1 - Multi-level droplet routing in active-matrix based digital-microfluidic biochips
AU - Lu, Guan Ruei
AU - Bhattacharya, Bhargab B.
AU - Ho, Tsung Yi
AU - Chen, Hung-Ming
PY - 2018/2/20
Y1 - 2018/2/20
N2 - Active-Matrix (AM) technology is currently being used to implement a superior class of EWOD-based biochips, which consist of a dense 2D-array of microelectrodes. These chips offer many advantages over conventional biochips such as the capability of handling variable-size droplets, more flexibility in droplet movement, precise control over droplet navigation, and as a sequel, ease of implementing complex bioprotocols on-chip. However, the new technology poses a number of challenges concerning droplet routing. In order to enhance routability, we propose, in this paper, a multi-level hierarchical approach that takes appropriate decisions on droplet splitting and reshaping. Compared to the most recent routing methods used for EWOD, the proposed multi-level router reduces maximum latest-arrivaltime by an average 18% and achieves 7% less average latest-arrival-time.
AB - Active-Matrix (AM) technology is currently being used to implement a superior class of EWOD-based biochips, which consist of a dense 2D-array of microelectrodes. These chips offer many advantages over conventional biochips such as the capability of handling variable-size droplets, more flexibility in droplet movement, precise control over droplet navigation, and as a sequel, ease of implementing complex bioprotocols on-chip. However, the new technology poses a number of challenges concerning droplet routing. In order to enhance routability, we propose, in this paper, a multi-level hierarchical approach that takes appropriate decisions on droplet splitting and reshaping. Compared to the most recent routing methods used for EWOD, the proposed multi-level router reduces maximum latest-arrivaltime by an average 18% and achieves 7% less average latest-arrival-time.
UR - http://www.scopus.com/inward/record.url?scp=85045310667&partnerID=8YFLogxK
U2 - 10.1109/ASPDAC.2018.8297281
DO - 10.1109/ASPDAC.2018.8297281
M3 - Conference contribution
AN - SCOPUS:85045310667
T3 - Proceedings of the Asia and South Pacific Design Automation Conference, ASP-DAC
SP - 46
EP - 51
BT - ASP-DAC 2018 - 23rd Asia and South Pacific Design Automation Conference, Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 22 January 2018 through 25 January 2018
ER -