Multi-layer planar micro-coils chip as actuators and heaters for biological applications

Chen Chia Chen*, Shih Hsun Hsu, Chen Hsiang Sang, Chih Chyau Yang, Chien Ming Wu, Chun Ming Huang, Jeng-Tzong Sheu

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, a multi-functional of multi-layer planar micro-coils chip is demonstrated to play as actuators and heaters. For playing as actuators, the micro-coil generate local magnetic field with applied current of 15 mA to quickly manipulated magnetic beads to center of micro-coil within one minute. For functioning as heaters, the micro-coil heater can be quickly heated up to denatured temperature of 95 °C with input power of 50.5 mW, and its heating and cooling rate are 19.7 and 11.8 °C/s, respectively. For the typical 25 polymerase chain reaction (PCR) cycles, it took only 770 seconds. To further shrink and optimize the multi-layer planar micro-coils chip can be possibly used to manipulate single cell with magnetic beads to specific region and analyze its gene sequence by using single cell PCR technique.

Original languageEnglish
Title of host publication2012 IEEE Biomedical Circuits and Systems Conference
Subtitle of host publicationIntelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications
Pages392-395
Number of pages4
DOIs
StatePublished - 1 Dec 2012
Event2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Hsinchu, Taiwan
Duration: 28 Nov 201230 Nov 2012

Publication series

Name2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications

Conference

Conference2012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012
CountryTaiwan
CityHsinchu
Period28/11/1230/11/12

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