Microbial synthesis of n-butanol, isobutanol, and other higher alcohols from diverse resources

Ethan I. Lan, James C. Liao*

*Corresponding author for this work

Research output: Contribution to journalArticle

130 Scopus citations

Abstract

Microbial production of fuel and chemical feedstock is a promising approach to solving energy and environmental problems. n-Butanol, isobutanol and other higher alcohols are of particular interest because they can serve as both fuel and chemical feedstock. Alternative resources such as CO2, syngas, waste protein, and lignocellulose are currently being investigated for their potential to produce these compounds. Except for lignocellulose, utilization of such alternative resource has not been examined extensively. This review aims to summarize the development of metabolic pathways for efficient synthesis of these higher alcohols and the current status of microbial strain development for the conversion of diverse resources into higher alcohols.

Original languageEnglish
Pages (from-to)339-349
Number of pages11
JournalBioresource Technology
Volume135
DOIs
StatePublished - 1 Jan 2013

Keywords

  • Alternative feedstock
  • Biofuel
  • Metabolic engineering
  • Renewable energy
  • Synthetic biology

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