Manufacturing of functional gelatin/chitosan composite membrane

Ching Wen Lou, Jin-Jia Hu*, Chao Tsang Lu, Chao Chiung Huang, Ming Sheng Huang, Jia Horng Lin

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

Biodegradable materials have gained more and more attention, especially in biomedical fields. Because of their degradability, biomedical products made of these biodegradable materials can reduce the deleterious impact to the environment. Among other biodegradable polymers, gelatin has been used in wound dressing to accelerate wound healing due to its biocompatibility, film formability and hemostatic activity. In this study, we used gelatin as the matrix for our dressing. As gelatin is prone to degrade/dissolve in water at body temperature, it has to be cross-linked or stabilized with other compounds to enhance its lifetime. Chitosan, another biodegradable polymer, is also widely used in wound healing due to its biocompatibility and antibacterial properties. In this study, we mixed gelatin solution with chitosan solution at a variety of ratios and tested the effectiveness of UV irradiation on cross-linking the two polymers. The composite membranes were fabricated and underwent tests of swelling, stability in water, water contact angle to evaluate their stability and hydrophilicity. Our results showed that the composite membrane made of gelatin/chitosan (90:10) treated with UV irradiation for ten min has the optimal stability in water.

Original languageEnglish
Title of host publicationApplications of Engineering Materials
Pages150-153
Number of pages4
DOIs
StatePublished - 12 Aug 2011
Event2011 International Conference on Advanced Engineering Materials and Technology, AEMT 2011 - Sanya, China
Duration: 29 Jul 201131 Jul 2011

Publication series

NameAdvanced Materials Research
Volume287-290
ISSN (Print)1022-6680

Conference

Conference2011 International Conference on Advanced Engineering Materials and Technology, AEMT 2011
CountryChina
CitySanya
Period29/07/1131/07/11

Keywords

  • Chitosan
  • Gelatin
  • Membrane
  • UV light

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