Low-Volume Fluorescence Detector for High-Performance Liquid Chromatography

Alain Berthod, Kuang Pang Li, Tiing Yu, James D. Winefordner*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The need for a variety of suitable detection techniques has induced many researchers to develop detectors for highperformance liquid chromatography (HPLC) (1–3), We have developed a fluorescence windowless flow cell by using a laser as the excitation source (4) and, more recently, we have evaluated the performance of a multiwavelength fluorescence detector by using a xenon lamp (5). The aim of the present work was to evaluate the capability of an extremely simple fluorescence detector based upon a commercial, inexpensive, low dead volume chromatographic tee.

Original languageEnglish
Pages (from-to)1485-1488
Number of pages4
JournalAnalytical Chemistry
Issue number10
StatePublished - 1 Jan 1987

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