Live circulating tumor cells selection on self-assembled cell array (SACA) chip by in-parallel image analysis and in-situ cell capture

Ming Hsuan Chiu, Yi Hsuan Weng, Hsin Ying Chen, Wan Ying Cho, Hsueh Yao Chu, Tsung Ju Chen, Song Sheng Yang, Ju Yu Tseng, Chien Ping Lin, Chih Yung Yang, Chi Hung Lin, Jeng Kai Jiang, Fan Gang Tseng*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study reports the rapid selection of identified live CTCs from whole blood on SACA chip for further characterization by automatic imaging and in-situ cell capturing process. The whole process takes 120 minutes for examining 4 ml whole blood sample and the recognition sensitivity can approach 1/108 by using the integrated chip and automatic image system. All cells are remained highly viable after the rapid selection process for further applications.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages278-279
Number of pages2
ISBN (Electronic)9780979806490
StatePublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 9 Oct 201613 Oct 2016

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Conference

Conference20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period9/10/1613/10/16

Keywords

  • Cell capture
  • Circulating tumor cells
  • SACA chip

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