Joined use of oxazolidinone and desymmetric amino protection: a new strategy for protection of glucosamine

Shih Che Lin, Chin Sheng Chao, Chiu Ching Chang, Kwok-Kong Mong*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Joined use of N-benzyl oxazolidinone and N-benzyl-N-benzyloxycarbonyl (N-BnCbz) desymmetric amino-protecting function is reported. The new synthetic approach enables the facile preparation of type 1 and type 2 LacNAc disaccharides in satisfactory yields. One-pot deprotection of N-BnCbz and O-benzyl ether is achieved by hydrogenolysis under mild conditions.

Original languageEnglish
Pages (from-to)1910-1913
Number of pages4
JournalTetrahedron Letters
Volume51
Issue number14
DOIs
StatePublished - 7 Apr 2010

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