Users play games because of fun and relaxation. But some users engage in the online game world, and they give up their educational or work opportunity and neglect their duties. These persons have the symptoms of Internet gaming disorder (IGD). Individual with IGD plays different online game scenes with dynamically psychophysiological control for a long period of time. However, the empirical studies focus on the long period of playing experiences or the short period of physiological responses for investigating the psychophysiological properties of IGD. Few studies discuss the instantaneous psychophysiological responses of persons with IGD. Moreover, individual differences in reaction time may influence the time-variate properties of IGD. It makes investigation of instantaneous psychophysiological responses more difficult. On the basis of the concept of multi-modal pressure-flow method, we propose an index of instantaneous phase delay (IPD) as a modulation of time for observing the instantaneous coordination of respiratory wall movement during watching game video. 19 and 21 persons with high-risk IGD (HIGD) and low-risk IGD (LIGD) were participant in this study, respectively. Preliminary result shows the negative correlation between the IGD questionnaires and IPD (within 3 cycles). Our finding indicated that individuals with HIGD may rapidly modulate psychophysiological response during negative game stimuli compared with individuals with LIGD. We suggested that IPD may be an potential index to assess IGD within 3 cycles. The findings should make an important contribution to advance the understanding of instantaneous regulation mechanism for IGD. Recruiting more participles is needed to verify this finding in the near future.