Influence of porous microarchitecture on the in-vitro dissolution and biological behaviour of porous calcium phosphate ceramics

Dean-Mo Liu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Calcium phosphate ceramics (CPC) have been received worldwide attention in commerce and health over the past few decades. Recently, the application of CPCs, particularly in a porous configuration, in clinic primarily as hard tissue replacement, repair, regeneration, and reconstruction and other uses such as controlled release drug carriers has attracted much attention and a great improvement in bioperformance in living tissue has been reported. However, controversies arising from a vast number of published reports concerning both in vitro and in vivo behaviors in relation to the chemical and physical properties of the porous CPCs are still unresolved. This paper reviews the in vitro dissolution and in vivo performance of the porous CPCs associated with the porous microarchitecture of the CPCs.

Original languageEnglish
Pages (from-to)183-208
Number of pages26
JournalMaterials Science Forum
Volume250
DOIs
StatePublished - 1 Dec 1997

Keywords

  • Bone Ingrowth
  • Calcium Phosphate Ceramic
  • Dissolution Kinetics
  • Histological Assessment
  • In Vitro Dissolution
  • In Vivo Performance
  • Microporosity
  • Porous Ceramic

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