In situ synthesis of hybrid nanocomposite with highly order arranged amorphous metallic copper nanoparticle in poly(2-hydroxyethyl methacrylate) and its potential for blood-contact uses

Yen Yu Liu, Dean-Mo LIu*, San-Yuan Chen, Tsan Hua Tung, Tse Ying Liu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

A hybrid consisting of a highly ordered nanostructure of metallic Cu(0) nanoparticles embedded in a poly(2-hydroxyethyl methacrylate) (pHEMA) matrix was successfully synthesized by in situ photopolymerization, followed by in situ chemical reduction. The evolution of an ordered nanostructure of Cu(0) showing a nearly amorphous nature is discussed, and it is proposed that it is due to a coupling interaction between the Cu precursor and the unpaired O of the COOR group, associated with water molecules, among pHEMA molecules. The hybrids showed a negative surface charge and considerable improvement in blood compatibility compared to neat pHEMA and the widely used biomaterial polysulfonate.

Original languageEnglish
Pages (from-to)2052-2058
Number of pages7
JournalActa Biomaterialia
Volume4
Issue number6
DOIs
StatePublished - 1 Nov 2008

Keywords

  • Copper nanoparticles
  • Cupric oxide
  • Hybrid
  • pHEMA
  • Surface charge

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