Implementation and evaluation of slow-time golay decoding for pre-clinical high-frequency color doppler imaging in mice

Che Chou Shen, Jyun Gong Yu, Gency Jeng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Golay Complementary Sequence (GCS) is conventionally regarded as not applicable to blood flow detection due to potential side-lobe motion artifact in the decoding. In our previous study, it has been shown that GCS decoding can be performed by low-pass filtering in slow-time Doppler domain with cutoff frequency of PRF/4 to alleviate the motion artifact. In this work, the proposed GCS Doppler decoding has been implemented in a pre-clinical high-frequency ultrasound imaging system to study the color Doppler quality and signal-to-noise ratio (SNR) using phantom and in-vivo experiments. The phantom results show that, when the Doppler shift is within ±PRF/4, the GCS provides comparable Doppler information to conventional un-coded method while the SNR improves. The in-vivo results also demonstrate that Doppler penetration increases from 13.5 mm to 14.2 mm in the mouse's kidney. For the abdominal aorta, GCS Doppler also enables the increase of transmit frequency from 30 MHz to 35 MHz to detect blood flow.

Original languageEnglish
Title of host publication2015 IEEE International Ultrasonics Symposium, IUS 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479981823
DOIs
StatePublished - 13 Nov 2015
EventIEEE International Ultrasonics Symposium, IUS 2015 - Taipei, Taiwan
Duration: 21 Oct 201524 Oct 2015

Publication series

Name2015 IEEE International Ultrasonics Symposium, IUS 2015

Conference

ConferenceIEEE International Ultrasonics Symposium, IUS 2015
CountryTaiwan
CityTaipei
Period21/10/1524/10/15

Keywords

  • Doppler
  • filtering
  • Golay Complementary Sequence
  • high frequency ultrasound imaging system
  • motion artifact
  • PRF/4

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