Idiopathic hypertrophic cardiomyopathy in identical twins; Morphological heterogeneity of the left ventricle

Y. L. Ko, T. K. Tang, J. J. Chen, Y. Y. Hshieh, C. W. Wu, W. P. Lien*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

We report a pair of identical twins with HC with varying extent of left ventricular hypertrophy and some degree of left ventricular outflow tract obstruction. The diagnosis of identical twins was based on the same sex, blood typings, HLA typings and hybridization patterns to four hypervariable DNA probes. Identical twins are derived from a single zygote and are genetically homogeneous human beings. The present report suggests that heterogeneity in the morphologic expression of HC may not be solely attributed to genetic factors. Environmental factors also may play an important role.

Original languageEnglish
Pages (from-to)783-785
Number of pages3
JournalChest
Volume102
Issue number3
DOIs
StatePublished - 1 Jan 1992

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