Hybrid semiconducting polymer dot-quantum dot with narrow-band emission, near-infrared fluorescence, and high brightness

Yang-Hsiang Chan, Fangmao Ye, Maria Elena Gallina, Xuanjun Zhang, Yuhui Jin, I. Che Wu, Daniel T. Chiu*

*Corresponding author for this work

Research output: Contribution to journalArticle

89 Scopus citations

Abstract

This communication describes a new class of semiconducting polymer nanoparticle-quantum dot hybrid with high brightness, narrow emission, near-IR fluorescence, and excellent cellular targeting capability. Using this approach, we circumvented the current difficulty with obtaining narrow-band-emitting and near-IR-fluorescing semiconducting polymer nanoparticles while combining the advantages of both semiconducting polymer nanoparticles and quantum dots. We further demonstrated the use of this new class of hybrid nanomaterial for effective and specific cellular and subcellular labeling without any noticeable nonspecific binding. This hybrid nanomaterial is anticipated to find use in a variety of in vitro and in vivo biological applications.

Original languageEnglish
Pages (from-to)7309-7312
Number of pages4
JournalJournal of the American Chemical Society
Volume134
Issue number17
DOIs
StatePublished - 2 May 2012

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